| Gravity Reactor Pilot | Under Construction | Other | Deep Fission | KS | 15 MW | 2026 |
| Molten Salt Research Reactor (MSRR) | Under Construction | Advanced Non-LWR | Natura Resources | TX | 1 MW | 2026 |
| RELLIS Pilot Bryan | Under Construction | Other | Last Energy | TX | 5 MW | 2026 |
| Hermes I Oak Ridge | Under Construction | Advanced Non-LWR | Kairos Power | TN | 35 MW | 2027 |
| Oklo Aurora - INL Idaho Falls | Under Construction | Other | Oklo Inc. | ID | 1.5 MW | 2027 |
| Project Pele Idaho Falls | Under Construction | Microreactor | US Department of Defense | ID | — | 2027 |
| Natrium - Kemmerer Kemmerer | Under Construction | Advanced Non-LWR | TerraPower | WY | 345 MW | 2031 |
| Hermes 2 Oak Ridge | Under Construction | Advanced Non-LWR | Kairos Power | TN | 50 MW | TBD |
| MARVEL microreactor | Under Construction | Microreactor | — | ID | — | — |
| Molten Chloride Reactor Experiment | Under Construction | Other | TerraPower | ID | — | — |
| Radiant Kaleidos Demonstration Unit in INL DOME | Under Construction | Microreactor | Radiant Industries | ID | 1 MW | — |
| TRISO-X TX-1 (X-energy) Oak Ridge | Under Construction | | — | TN | — | — |
| Palisades Nuclear Plant Covert | Restarting | Reactor Restart | Holtec International | MI | 800 MW | 2026 |
| Crane Clean Energy Center (TMI-1 Restart) Middletown | Restarting | Reactor Restart | Constellation Energy | PA | 835 MW | 2028 |
| Duane Arnold Energy Center restart | Restarting | Reactor Restart | — | IA | 615 MW | — |
| Orano Project IKE enrichment plant Oak Ridge | Pre-Licensing | | — | TN | — | — |
| Savannah River Site H-Canyon Aiken | Pre-Licensing | | — | SC | — | — |
| Project Tetra | Project Planning | Advanced Non-LWR | Terrestrial Energy | TX | 392 MW | 2026 |
| Eielson AFB Microreactor Fairbanks | Project Planning | Microreactor | — | AK | 0.1 MW | 2028 |
| Standard Power / ENTRA 1 SMR | Project Planning | SMR (LWR) | Standard Power | — | 800 MW | 2029 |
| Cascade Energy Facility Richland | Project Planning | Advanced Non-LWR | Energy Northwest / Amazon | WA | 320 MW | 2030 |
| Pike County Campus | Project Planning | Other | Oklo Inc. | OH | 1,200 MW | 2034 |
| Holtec SMR-160 | Project Planning | SMR (LWR) | Holtec International | NJ | 160 MW | 2035 |
| Buckley Space Force Base microreactor | Project Planning | Microreactor | — | CO | — | — |
| Elementl Power Meigs County nuclear plant | Project Planning | SMR (LWR) | Elementl | OH | — | — |
| Fort Benning microreactor | Project Planning | Microreactor | — | GA | — | — |
| Fort Bragg microreactor | Project Planning | Microreactor | — | NC | — | — |
| Fort Campbell microreactor | Project Planning | Microreactor | — | KY | 20 MW | — |
| Fort Drum microreactor | Project Planning | Microreactor | — | NY | — | — |
| Fort Hood microreactor | Project Planning | Microreactor | — | TX | 5 MW | — |
| General Matter enrichment plant Paducah | Project Planning | | — | KY | — | — |
| Joint Base San Antonio microreactor | Project Planning | Microreactor | — | TX | — | — |
| Joshua Falls SMR site | Project Planning | SMR (LWR) | — | VA | — | — |
| Last Energy Haskell County microreactor plant | Project Planning | Microreactor | Last Energy | TX | — | — |
| Malmstrom Air Force Base microreactor | Project Planning | Microreactor | — | MT | — | — |
| Naval Surface Warfare Center Crane / NWS Crane microreactor | Project Planning | Microreactor | — | IN | — | — |
| Nine Mile Point new nuclear Early Site Permit | Project Planning | SMR (LWR) | Constellation Energy | NY | — | — |
| Permian Basin MSR-100 (Natura) Permian Basin | Project Planning | | — | TX | — | — |
| Pioneer 1 and 2 | Project Planning | SMR (LWR) | Holtec International | — | 680 MW | — |
| Project Beehive (Valar) Price | Project Planning | | — | UT | — | — |
| Rockport SMR | Project Planning | SMR (LWR) | Indiana Michigan Power | IN | — | — |
| Texas A&M-RELLIS Energy Proving Ground | Project Planning | Advanced Non-LWR | — | TX | — | — |
| V.C. Summer Units 2 and 3 completion | Project Planning | Large LWR | — | SC | — | — |
| Aalo-X Demo - INL Scoville (INL) | Demo / Pilot | Microreactor | Aalo Atomics | ID | — | 2026 |
| Groves Isotopes Facility Idaho Falls | Demo / Pilot | Other | Oklo Inc. / Atomic Alchemy | TX | — | 2026 |
| Mark-0 | Demo / Pilot | Other | Antares | ID | — | 2026 |
| Pluto Test Facility | Demo / Pilot | Other | Oklo Inc. | — | — | 2026 |
| Unity Demo - INL Idaho Falls | Demo / Pilot | Other | Deployable Energy | ID | 1 MW | 2026 |
| Utah San Rafael Energy Center Green River | Demo / Pilot | Other | Valar | UT | 0.1 MW | 2026 |
| BWXT Advanced Fuels Lynchburg | Operational | | — | VA | — | — |
| Centrus American Centrifuge Plant (HALEU) Piketon | Operational | | — | OH | — | — |
| Clinton Clean Energy Center (Meta uprate/extension) Clinton | Operational | | — | IL | — | — |
| Framatome Richland fuel plant Richland | Operational | | — | WA | — | — |
| Metropolis Works (ConverDyn) Metropolis | Operational | | — | IL | — | — |
| Nuclear Fuel Services (BWXT) Erwin | Operational | | — | TN | — | — |
| Standard Nuclear TRISO plant Oak Ridge | Operational | | — | TN | — | — |
| Susquehanna (Talen-Amazon data center + SMR exploration) Salem Township | Operational | | — | PA | — | — |
| Urenco USA National Enrichment Facility Eunice | Operational | | — | NM | — | — |
| Westinghouse Columbia Fuel Fabrication Facility Columbia | Operational | | — | SC | — | — |
| North Anna 3 Mineral | On Hold | Other | Dominion Energy | VA | 1,500 MW | — |
| Paducah Gaseous Diffusion Plant (DOE host site) Paducah | On Hold | | — | KY | — | — |
| NANO Nuclear - UIUC Urbana | NRC Review | Other | NANO Nuclear Energy | IL | 5 MW | 2028 |
| Port of Victoria Victoria | NRC Review | Other | Blue Energy | TX | 1,500 MW | 2028 |
| Long Mott Energy Project (Dow) Seadrift | NRC Review | Advanced Non-LWR | Long Mott Energy (Dow Chemical subsidiary) | TX | 320 MW | 2030 |
| Palisades SMRs Covert | NRC Review | SMR (LWR) | Holtec International | MI | 600 MW | 2030 |
| Project Matador Carson County (NE of Amarillo) | NRC Review | Large LWR | Fermi America | TX | 4,400 MW | 2031 |
| Clinch River SMR (TVA) Oak Ridge | Permit Issued | SMR (LWR) | Tennessee Valley Authority | TN | 300 MW | 2033 |
| Belews Creek SMR Walnut Cove | NRC Review | SMR (LWR) | Duke Energy | NC | — | 2034 |
| North Anna SMR / North Anna Early Site Permit renewal | NRC Review | SMR (LWR) | — | VA | — | — |
| Paducah Laser Enrichment Facility (GLE) Paducah | NRC Review | | — | KY | — | — |
| Salem-Hope Creek new-build ESP (PSEG) Hancocks Bridge | NRC Review | | — | NJ | — | — |